Atopic dermatitis is the one of the most common chronic skin disease in children. This condition usually appears 2 months after birth, causing dry, itchy, cracked and inflamed skin. As children grow
The skin is the largest organ in the human body, and it bears the weighty responsibility of protecting the body from environmental pathogens and irritants. If the skin’s protective capabilities are compromised, its ability to defend the body decreases, which allows environmental allergens to invade and induce immune inflammation responses. Damaged epidermis allows moisture to be continuously lost, which causes dryness and itching. Scratching then further damages the skin, which in-turn stimulates immune cells and causes inflammation to recur, forming a vicious circle. It can even result in bacterial infections.
Most babies with atopic dermatitis begin to have outbreaks when they are 2 to 3 months old. Outbreaks of atopic dermatitis cause cheeks to become dry, red, scaly, and extremely itchy. The discomfort makes babies restless, and they then have difficulty falling asleep. Although atopic dermatitis is not caused by a single gene, research has found that the disease is related to several significant genetic factors. In addition, while the skin of high-risk infants has the same moisture retention ability as that of normal infants at birth, by 2 months, a significant difference is apparent. As the protective layer of the skin becomes progressively more damaged, the dry skin of high-risk infants becomes worse.
Although the genetic result cannot be changed after birth, according the current researches, the number of penetrated antigen can be reduced by moisturizers and emollients before the first outbreak to elevate the skin barrier function and prevent transepidermal water loss, and decrease more than 30% of the incidence rate.
Step1：Discuss with your doctor and fill the consent form as well.
Step2：Using 2 swaps to collect enough oral mucosal cells.
Step3：The sample is sent to a newborn screening laboratory.
Step4：DNA will be extracted from the sample for screening.
Step5：The report will be given in 21 working days.